Manganese as a Chemotherapeutic Agent.

Chemotherapeutic Agent for Glioma

Synthesis and evaluation of chitosan manganese-ferrite nanoparticles as MRI contrast agent

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

Fosmidomycin, a novel chemotherapeutic agent for malaria.

In previous studies, fosmidomycin has been shown to possess activity against Plasmodium falciparum in vitro and in the mouse model. It has a novel mode of action through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase, an enzyme of the nonmevalonate pathway of isoprenoid biosynthesis, which is absent in humans. In this open-label, uncontrolled trial, the efficacy and safety of fos...

Synthesis and evaluation of chitosan manganese-ferrite nanoparticles as MRI contrast agent

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

Sintering Behavior of Forsterite with Manganese Oxide as Doping Agent

Forsterite (Mg2SiO4) powder was synthesized using magnesium and talc with assistance of ball milling. Manganese doped forsterite was prepared at weight percentage of 0.05%, 0.1%, 0.2%, 0.5% and 1.0wt% by adding manganese oxide before ball milling. The undoped and manganese doped forsterite were sintered at temperature of 1000°C, 1100°C and 1200°C. The Vickers hardness, fracture toughness and Yo...